Abstract

A new method for identifying secretory signal sequences and for predicting the site of cleavage between a signal sequence and the mature exported protein is described. The predictive accuracy is estimated to be around 75-80% for both prokaryotic and eukaryotic proteins.

Keywords

BiologyCleavage (geology)Sequence (biology)Library scienceGeneticsComputer sciencePaleontology

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Publication Info

Year
1986
Type
article
Volume
14
Issue
11
Pages
4683-4690
Citations
4552
Access
Closed

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Gunnar von Heijne (1986). A new method for predicting signal sequence cleavage sites. Nucleic Acids Research , 14 (11) , 4683-4690. https://doi.org/10.1093/nar/14.11.4683

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DOI
10.1093/nar/14.11.4683