Keywords
BiologyCleavage (geology)DNAMethyltransferaseBinding siteDNA methyltransferaseMolecular biologyBiochemistryMethylation
Affiliated Institutions
Related Publications
X inactivation, differentiation, and DNA methylation
A model based on DNA methylation is proposed to explain the initiation and maintenance of mammalian X inactivation and certain aspects of other permanent events in eukaryotic ce...
The DNA methyltransferases of mammals
The biological significance of 5-methylcytosine was in doubt for many years, but is no longer. Through targeted mutagenesis in mice it has been learnt that every protein shown b...
Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells
We have shown previously that de novo methylation activities persist in mouse embryonic stem (ES) cells homozygous for a null mutation of Dnmt1 that encodes the major DNA cytosi...
Methylation hot spots in the 5' flanking region denote silencing of the O6-methylguanine-DNA methyltransferase gene.
The mechanism whereby the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) is silenced in repair-deficient (Mer-) human tumor cells is unknown. The role of methy...
An expansive human regulatory lexicon encoded in transcription factor footprints
Regulatory factor binding to genomic DNA protects the underlying sequence from cleavage by DNase I, leaving nucleotide-resolution footprints. Using genomic DNase I footprinting ...
Publication Info
- Year
- 1992
- Type
- article
- Volume
- 11
- Issue
- 7
- Pages
- 2611-2617
- Citations
- 454
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
454
OpenAlex
Cite This
Timothy H. Bestor
(1992).
Activation of mammalian DNA methyltransferase by cleavage of a Zn binding regulatory domain..
The EMBO Journal
, 11
(7)
, 2611-2617.
https://doi.org/10.1002/j.1460-2075.1992.tb05326.x
Identifiers
- DOI
- 10.1002/j.1460-2075.1992.tb05326.x