Abstract

The BCR-ABL tyrosine kinase inhibitor STI571 is well tolerated and has substantial activity in the blast crises of CML and in Ph-positive ALL.

Keywords

MedicinePhiladelphia chromosomeMyeloid leukemiaTyrosine-kinase inhibitorInternal medicineMyeloidTyrosine kinaseLeukemiaImmunologyCancer researchChromosomal translocationCancerBiology

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Publication Info

Year
2001
Type
article
Volume
344
Issue
14
Pages
1038-1042
Citations
2710
Access
Closed

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Brian Druker, Charles L. Sawyers, Hagop M. Kantarjian et al. (2001). Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome. New England Journal of Medicine , 344 (14) , 1038-1042. https://doi.org/10.1056/nejm200104053441402

Identifiers

DOI
10.1056/nejm200104053441402