Keywords
MedicineAngiotensin-converting enzyme 2Peptidyl-Dipeptidase ASevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pain medicineCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakAnesthesiologyAngiotensin-converting enzymeRenin–angiotensin systemReceptorEnzymePharmacologyInternal medicineVirologyAnesthesiaBlood pressureBiochemistryDiseaseBiologyInfectious disease (medical specialty)
Affiliated Institutions
Related Publications
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
How SARS-CoV-2 binds to human cells Scientists are racing to learn the secrets of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), which is the cause of the pandemi...
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
The outbreak of a novel coronavirus (2019-nCoV) represents a pandemic threat that has been declared a public health emergency of international concern. The CoV spike (S) glycopr...
Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus
The recent emergence of Wuhan coronavirus (2019-nCoV) puts the world on alert. 2019-nCoV is reminiscent of the SARS-CoV outbreak in 2002 to 2003. Our decade-long structural stud...
Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2
The trimeric SARS coronavirus (SARS-CoV) surface spike (S) glycoprotein consisting of three S1-S2 heterodimers binds the cellular receptor angiotensin-converting enzyme 2 (ACE2)...
Publication Info
- Year
- 2020
- Type
- article
- Volume
- 46
- Issue
- 4
- Pages
- 586-590
- Citations
- 2771
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
2771
OpenAlex
Cite This
Haibo Zhang,
Josef Penninger,
Yimin Li
et al.
(2020).
Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target.
Intensive Care Medicine
, 46
(4)
, 586-590.
https://doi.org/10.1007/s00134-020-05985-9
Identifiers
- DOI
- 10.1007/s00134-020-05985-9