APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline

Axel Montagne; Daniel A. Nation; Abhay P. Sagare; Giuseppe Barisano; Melanie D. Sweeney; Ararat Chakhoyan; Maricarmen Pachicano; Elizabeth Joe; Amy R. Nelson; Lina M. D’Orazio; David P Buennagel; Michael G. Harrington; Tammie L.S. Benzinger; Anne M. Fagan; John M. Ringman; Lon S. Schneider; John C. Morris; Eric M. Reiman; Richard J. Caselli; Helena C. Chui; Julia TCW; Yining Chen; Judy Pa; Peter S. Conti; Meng Law; Arthur W. Toga; Berislav V. Zloković

doi:10.1038/s41586-020-2247-3

Keywords

Cognitive declineCerebrospinal fluidBiomarkerDementiaApolipoprotein EBlood–brain barrierNeurosciencePathologyHippocampusMedicinePsychologyDiseaseInternal medicineBiologyCentral nervous system

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Publication Info

Year: 2020
Type: article
Volume: 581
Issue: 7806
Pages: 71-76
Citations: 1125
Access: Closed

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APA Style

                            
                                
                                    Axel Montagne, 
                                
                                    Daniel A. Nation, 
                                
                                    Abhay P. Sagare
                                
                                et al.
                            
                            (2020). 
                            APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline. 
                            Nature
                            , 581
                            (7806)
                            , 71-76.
                            https://doi.org/10.1038/s41586-020-2247-3
                        

Identifiers

DOI: 10.1038/s41586-020-2247-3