Keywords
Salt bridgeMutantSide chainSalt (chemistry)RepressorChemistryCrystallographyProtein structureBiophysicsStereochemistryBiochemistryBiologyGene
Affiliated Institutions
Related Publications
Contributions of a hydrogen bond/salt bridge network to the stability of secondary and tertiary structure in λ repressor
Abstract In the N‐terminal domain of λ repressor, the Asp 14 side chain forms an intrahelical, hydrogen bond/salt bridge with the Arg 17 side chain and a tertiary hydrogen bond ...
Do salt bridges stabilize proteins? A continuum electrostatic analysis
Abstract The electrostatic contribution to the free energy of folding was calculated fo 21 salt bridges in 9 r X‐ray crystal structures using a continuum electrostatic approach ...
Protein-Protein Interfaces: Architectures and Interactions in Protein-Protein Interfaces and in Protein Cores. Their Similarities and Differences
Protein structures generally consist of favorable folding motifs formed by specific arrangements of secondary structure elements. Similar architectures can be adopted by differe...
Study of the stability and unfolding mechanism of BBA1 by molecular dynamics simulations at different temperatures
Abstract BBA1 is a designed protein that has only 23 residues. It is the smallest protein without disulfide bridges that has a well‐defined tertiary structure in solution. We ha...
Escherichia coli-derived rat intestinal fatty acid binding protein with bound myristate at 1.5 A resolution and I-FABPArg106—>Gln with bound oleate at 1.74 A resolution.
Rat intestinal fatty acid binding protein (I-FABP) is a 131-residue protein composed of two short alpha-helices (alpha I and alpha II) and 10 anti-parallel beta-strands organize...
Publication Info
- Year
- 1995
- Type
- article
- Volume
- 2
- Issue
- 2
- Pages
- 122-128
- Citations
- 323
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
323
OpenAlex
Cite This
Carey D. Waldburger,
Joel F. Schildbach,
Robert T. Sauer
(1995).
Are buried salt bridges important for protein stability and conformational specificity?.
Nature Structural & Molecular Biology
, 2
(2)
, 122-128.
https://doi.org/10.1038/nsb0295-122
Identifiers
- DOI
- 10.1038/nsb0295-122