Keywords
GeneGene predictionPseudogeneGenomeBiologyComputational biologyGeneticsSequence alignmentAlignment-free sequence analysisGene familyPeptide sequence
Affiliated Institutions
Related Publications
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
The sensitivity of the commonly used progressive multiple sequence alignment method has been greatly improved for the alignment of divergent protein sequences. Firstly, individu...
Generating consensus sequences from partialorder multiple sequence alignment graphs
Abstract Motivation: Consensus sequence generation is important in many kinds of sequence analysis ranging from sequence assembly to profile-based iterative search methods. Howe...
GeneMarkS: a self-training method for prediction of gene starts in microbial genomes. Implications for finding sequence motifs in regulatory regions
Improving the accuracy of prediction of gene starts is one of a few remaining open problems in computer prediction of prokaryotic genes. Its difficulty is caused by the absence ...
Evolutionary-scale prediction of atomic-level protein structure with a language model
Recent advances in machine learning have leveraged evolutionary information in multiple sequence alignments to predict protein structure. We demonstrate direct inference of full...
Rfam 11.0: 10 years of RNA families
The Rfam database (available via the website at http://rfam.sanger.ac.uk and through our mirror at http://rfam.janelia.org) is a collection of non-coding RNA families, primarily...
Publication Info
- Year
- 2014
- Type
- article
- Volume
- 15
- Issue
- 1
- Pages
- 189-189
- Citations
- 60
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
60
OpenAlex
Cite This
Osamu Gotoh,
Masato Morita,
David R. Nelson
(2014).
Assessment and refinement of eukaryotic gene structure prediction with gene-structure-aware multiple protein sequence alignment.
BMC Bioinformatics
, 15
(1)
, 189-189.
https://doi.org/10.1186/1471-2105-15-189
Identifiers
- DOI
- 10.1186/1471-2105-15-189