Abstract

H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials.

Keywords

DiseaseMedicineMEDLINEIntensive care medicineBiologyPathology

MeSH Terms

AnimalsDisease ModelsAnimalHumansPublication BiasReproducibility of ResultsTranslational ResearchBiomedical

Affiliated Institutions

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Publication Info

Year
2010
Type
article
Volume
7
Issue
3
Pages
e1000245-e1000245
Citations
1276
Access
Closed

External Links

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1276
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11
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1034
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Cite This

H. Bart van der Worp, David W. Howells, Emily S. Sena et al. (2010). Can Animal Models of Disease Reliably Inform Human Studies?. PLoS Medicine , 7 (3) , e1000245-e1000245. https://doi.org/10.1371/journal.pmed.1000245

Identifiers

DOI
10.1371/journal.pmed.1000245
PMID
20361020
PMCID
PMC2846855

Data Quality

Data completeness: 86%