Abstract

Over the past ten years, numerous chemokines have been identified as attractants of different types of blood leukocytes to sites of infection and inflammation. They are produced locally in the tissues and act on leukocytes through selective receptors. Chemokines are now known to also function as regulatory molecules in leukocyte maturation, traffic and homing of lymphocytes, and the development of lymphoid tissues.

Keywords

Homing (biology)ChemokineLeukocyte TraffickingInflammationImmunologyChemokine receptorReceptorLymphocyte homing receptorFunction (biology)BiologyCell biologyCellCell adhesionGeneticsEcology

MeSH Terms

ChemokinesChemotaxisLeukocyteForecastingHomeostasisHumansHypersensitivityLymphocytesLymphoid TissueReceptorsChemokineT-Lymphocytes

Affiliated Institutions

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Publication Info

Year
1998
Type
review
Volume
392
Issue
6676
Pages
565-568
Citations
2712
Access
Closed

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2712
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96
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2138
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Cite This

Marco Baggiolini (1998). Chemokines and leukocyte traffic. Nature , 392 (6676) , 565-568. https://doi.org/10.1038/33340

Identifiers

DOI
10.1038/33340
PMID
9560152

Data Quality

Data completeness: 81%