ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

Abstract

Abstract Summary: We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term network. It can analyze one or compare two lists of genes and comprehensively visualizes functionally grouped terms. A one-click update option allows ClueGO to automatically download the most recent GO/KEGG release at any time. ClueGO provides an intuitive representation of the analysis results and can be optionally used in conjunction with the GOlorize plug-in. Availability: http://www.ici.upmc.fr/cluego/cluegoDownload.shtml Contact: jerome.galon@crc.jussieu.fr Supplementary information: Supplementary data are available at Bioinformatics online.

Keywords

DECIPHERKEGGPlug-inAnnotationComputer scienceGene ontologyOntologyGene AnnotationRepresentation (politics)Computational biologyInformation retrievalBioinformaticsGeneBiologyArtificial intelligenceGenomeProgramming languageGeneticsGene expression

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Publication Info

Year: 2009
Type: article
Volume: 25
Issue: 8
Pages: 1091-1093
Citations: 6398
Access: Closed

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APA Style

                            
                                
                                    Gabriela Bindea, 
                                
                                    Bernhard Mlecnik, 
                                
                                    Hubert Hackl
                                
                                et al.
                            
                            (2009). 
                            ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks. 
                            Bioinformatics
                            , 25
                            (8)
                            , 1091-1093.
                            https://doi.org/10.1093/bioinformatics/btp101
                        

Identifiers

DOI: 10.1093/bioinformatics/btp101