Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

Bart De Strooper; Paul Säftig; Katleen Craessaerts; Hugo Vanderstichele; Gundula Guhde; Wim Annaert; Kurt Von Figura; F. Van Leuven

doi:10.1038/34910

Keywords

PresenilinAmyloid precursor proteinProteolysisTransmembrane domainP3 peptideExtracellularTransmembrane proteinCleavage (geology)Cell biologyAmyloid precursor protein secretaseChemistryAlpha secretaseAlzheimer's diseasePeptideMembrane proteinBiochemistryBiologyGeneInternal medicineMembraneEnzymeDiseaseMedicine

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Publication Info

Year: 1998
Type: article
Volume: 391
Issue: 6665
Pages: 387-390
Citations: 1806
Access: Closed

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APA Style

                            
                                
                                    Bart De Strooper, 
                                
                                    Paul Säftig, 
                                
                                    Katleen Craessaerts
                                
                                et al.
                            
                            (1998). 
                            Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein. 
                            Nature
                            , 391
                            (6665)
                            , 387-390.
                            https://doi.org/10.1038/34910
                        

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DOI: 10.1038/34910