Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

2014 The Lancet 2,602 citations

Abstract

UK Medical Research Council, British Heart Foundation, University of Glasgow, University of Edinburgh.

Keywords

MedicineThrombolysisStroke (engine)Fibrinolytic agentRandomized controlled trialMeta-analysisIschaemic strokeOdds ratioPlaceboInternal medicineSurgeryTissue plasminogen activatorPhysical therapyIschemiaMyocardial infarction

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Publication Info

Year
2014
Type
review
Volume
384
Issue
9958
Pages
1929-1935
Citations
2602
Access
Closed

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2602
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Jonathan Emberson, Kennedy R. Lees, Patrick D. Lyden et al. (2014). Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials. The Lancet , 384 (9958) , 1929-1935. https://doi.org/10.1016/s0140-6736(14)60584-5

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DOI
10.1016/s0140-6736(14)60584-5