Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke

Joseph P. Broderick; Yuko Y. Palesch; Andrew M. Demchuk; Sharon D. Yeatts; Pooja Khatri; Michael D. Hill; Edward C. Jauch; Tudor G. Jovin; Bernard Yan; Frank L. Silver; Rüdiger von Kummer; Carlos A. Molina; Bart M. Demaerschalk; Ronald F. Budzik; Wayne M. Clark; Osama O. Zaidat; Tim W. Malisch; Mayank Goyal; Wouter J. Schonewille; Mikaël Mazighi; Stefan T. Engelter; Craig S. Anderson; Judith Spilker; Janice Carrozzella; Karla J. Ryckborst; L. Scott Janis; Renée H. Martin; Lydia D. Foster; Thomas A. Tomsick

doi:10.1056/nejmoa1214300

Abstract

The trial showed similar safety outcomes and no significant difference in functional independence with endovascular therapy after intravenous t-PA, as compared with intravenous t-PA alone. (Funded by the National Institutes of Health and others; ClinicalTrials.gov number, NCT00359424.).

Keywords

MedicineTissue plasminogen activatorIntravenous therapyStroke (engine)Ischemic strokeThrombolysisEndovascular treatmentAcute strokeInternal medicineAnesthesiaSurgeryIschemiaMyocardial infarctionAneurysm

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Publication Info

Year: 2013
Type: article
Volume: 368
Issue: 10
Pages: 893-903
Citations: 1789
Access: Closed

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APA Style

                            
                                
                                    Joseph P. Broderick, 
                                
                                    Yuko Y. Palesch, 
                                
                                    Andrew M. Demchuk
                                
                                et al.
                            
                            (2013). 
                            Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke. 
                            New England Journal of Medicine
                            , 368
                            (10)
                            , 893-903.
                            https://doi.org/10.1056/nejmoa1214300
                        

Identifiers

DOI: 10.1056/nejmoa1214300