Evidence for a Causal Association Between Human Papillomavirus and a Subset of Head and Neck Cancers

2000 JNCI Journal of the National Cancer Institute 3,058 citations

Abstract

These data extend recent molecular and epidemiologic studies and strongly suggest that HPV-positive oropharyngeal cancers comprise a distinct molecular, clinical, and pathologic disease entity that is likely causally associated with HPV infection and that has a markedly improved prognosis.

Keywords

Odds ratioIn situ hybridizationSouthern blotOncologyHazard ratioLymph nodeCancerInternal medicineHead and neck cancerHead and neck squamous-cell carcinomaConfidence intervalMedicinePathologyBiologyCancer researchGeneGeneticsGene expression

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Publication Info

Year
2000
Type
article
Volume
92
Issue
9
Pages
709-720
Citations
3058
Access
Closed

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Maura L. Gillison (2000). Evidence for a Causal Association Between Human Papillomavirus and a Subset of Head and Neck Cancers. JNCI Journal of the National Cancer Institute , 92 (9) , 709-720. https://doi.org/10.1093/jnci/92.9.709

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DOI
10.1093/jnci/92.9.709