Abstract
Meta-analyses aim to provide a full and comprehensive summary of related studies which have addressed a similar question. When the studies involve time to event (survival-type) data the most appropriate statistics to use are the log hazard ratio and its variance. However, these are not always explicitly presented for each study. In this paper a number of methods of extracting estimates of these statistics in a variety of situations are presented. Use of these methods should improve the efficiency and reliability of meta-analyses of the published literature with survival-type endpoints.
Keywords
StatisticsMeta-analysisReliability (semiconductor)Computer scienceSurvival analysisHazard ratioEvent (particle physics)EconometricsHazardVariance (accounting)Confidence intervalMathematicsMedicine
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Publication Info
- Year
- 1998
- Type
- article
- Volume
- 17
- Issue
- 24
- Pages
- 2815-2834
- Citations
- 4776
- Access
- Closed
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Cite This
Mahesh Parmar,
Valter Torri,
Lesley Stewart
(1998).
Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints.
Statistics in Medicine
, 17
(24)
, 2815-2834.
https://doi.org/10.1002/(sici)1097-0258(19981230)17:24<2815::aid-sim110>3.0.co;2-8
Identifiers
- DOI
- 10.1002/(sici)1097-0258(19981230)17:24<2815::aid-sim110>3.0.co;2-8