Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

Abstract

We identified at least one potential driver mutation in nearly all AML samples and found that a complex interplay of genetic events contributes to AML pathogenesis in individual patients. The databases from this study are widely available to serve as a foundation for further investigations of AML pathogenesis, classification, and risk stratification. (Funded by the National Institutes of Health.).

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Affiliated Institutions

• Brown University US
• University of British Columbia CA
• University of Southern California US
• The University of Texas MD Anderson Cancer Center US
• Johns Hopkins University US
• Washington University in St. Louis US
• University of North Carolina at Chapel Hill US
• Nationwide Children's Hospital US
• Seattle Cancer Care Alliance US
• Seattle University US
• Massachusetts Institute of Technology US
• National Institutes of Health US

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