GNAQ inhibits tumorigenesis via the ARHGEF25-mediated RHOA pathway in NK/T-cell lymphoma

Yuyang Gao; Zihe Zhang; Wenting Song; Hongwen Li; Lei Zhang; Zhaoming Li

doi:10.1080/15384047.2025.2598074

Abstract

In summary, RHOA is a critical downstream effector of GNAQ in NKTCL. GNAQ promotes RHOA activation through ARHGEF25, which in turn regulates cellular functions by modulating cell proliferation and apoptosis, thereby influencing the progression of NKTCL.

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Publication Info

Year: 2025
Type: article
Volume: 26
Issue: 1
Pages: 2598074-2598074
Citations: 0
Access: Closed

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APA Style

                            
                                
                                    Yuyang Gao, 
                                
                                    Zihe Zhang, 
                                
                                    Wenting Song
                                
                                et al.
                            
                            (2025). 
                            GNAQ inhibits tumorigenesis via the ARHGEF25-mediated RHOA pathway in NK/T-cell lymphoma. 
                            Cancer Biology & Therapy
                            , 26
                            (1)
                            , 2598074-2598074.
                            https://doi.org/10.1080/15384047.2025.2598074
                        

Identifiers

DOI: 10.1080/15384047.2025.2598074