Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer

Willemien J. van Driel , Simone N. Koole , Karolina Sikorska , Willemien J. van Driel , Simone N. Koole , Karolina Sikorska , Jules H. Schagen van Leeuwen , Henk W.R. Schreuder , Ralph H.M. Hermans , Ignace H. J. T. de Hingh , Jacobus van der Velden , Henriëtte J.G. Arts , Leon F.A.G. Massuger , Arend G. J. Aalbers , Victor J. Verwaal , Jacobien M. Kieffer , Koen Van de Vijver , Harm van Tinteren , Neil K. Aaronson , Gabe S. Sonke
2018 New England Journal of Medicine 1,329 citations

Abstract

Among patients with stage III epithelial ovarian cancer, the addition of HIPEC to interval cytoreductive surgery resulted in longer recurrence-free survival and overall survival than surgery alone and did not result in higher rates of side effects. (Funded by the Dutch Cancer Society; ClinicalTrials.gov number, NCT00426257 ; EudraCT number, 2006-003466-34 .).

Keywords

Intraperitoneal chemotherapyOvarian cancerHyperthermic intraperitoneal chemotherapyOncologyMedicineChemotherapyInternal medicineCancerCytoreductive surgery

Affiliated Institutions

Related Publications

Publication Info

Year
2018
Type
article
Volume
378
Issue
3
Pages
230-240
Citations
1329
Access
Closed

External Links

View on DOI.org

Social Impact

Altmetric
PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

1329
OpenAlex

Cite This

Willemien J. van Driel, Simone N. Koole, Karolina Sikorska et al. (2018). Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer. New England Journal of Medicine , 378 (3) , 230-240. https://doi.org/10.1056/nejmoa1708618

Identifiers

DOI
10.1056/nejmoa1708618