Abstract
The Gross cell surface antigen (GCSA) is produced by cells that are either exogenously infected with murine leukemia virus (MuLV) or are expressing endogenous MuLV genomes. In immune precipitation assays, GCSA was resolved into two serologically distinct 85,000- and 95,000-dalton viral proteins. These antigenic components are glycosylated forms of the polyprotein precursors of the MuLV internal structural proteins.
Keywords
BiologyAntigenVirologyMurine leukemia virusLeukemiaVirusEndogenyCellGenomeImmune systemMolecular biologyGeneImmunologyBiochemistry
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Publication Info
- Year
- 1977
- Type
- article
- Volume
- 23
- Issue
- 2
- Pages
- 315-322
- Citations
- 90
- Access
- Closed
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Cite This
J A Ledbetter,
Robert C. Nowinski
(1977).
Identification of the Gross cell surface antigen associated with murine leukemia virus-infected cells.
Journal of Virology
, 23
(2)
, 315-322.
https://doi.org/10.1128/jvi.23.2.315-322.1977
Identifiers
- DOI
- 10.1128/jvi.23.2.315-322.1977