Keywords
MacrophageImmunologyBiologyInflammationFunction (biology)MonocyteCell biologyGeneticsIn vitro
Affiliated Institutions
Related Publications
Macrophage plasticity, polarization, and function in health and disease
Macrophages are heterogeneous and their phenotype and functions are regulated by the surrounding micro‐environment. Macrophages commonly exist in two distinct subsets: 1) Classi...
The biologic importance of tumor‐infiltrating lymphocytes
Detailed pathologic analysis has delineated a close association between intratumoral CD 8 + cytotoxic T cells and favorable clinical outcomes in diverse cancers. Conversely, the...
Immune Regulation of Cancer
Innate and adaptive immune system cells play a major role in regulating the growth of cancer. Although it is commonly thought that an immune response localized to the tumor will...
bcl-2 inhibits apoptosis of neutrophils but not their engulfment by macrophages.
Neutrophils, the most common inflammatory leukocytes, have the most limited life span of all blood cells. After they undergo apoptosis, they are recognized and engulfed by macro...
Selective Roles for Toll-Like Receptor (TLR)2 and TLR4 in the Regulation of Neutrophil Activation and Life Span
Abstract Neutrophil responses to commercial LPS, a dual Toll-like receptor (TLR)2 and TLR4 activator, are regulated by TLR expression, but are amplified by contaminating monocyt...
Publication Info
- Year
- 2010
- Type
- review
- Volume
- 11
- Issue
- 10
- Pages
- 889-896
- Citations
- 3693
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
3693
OpenAlex
Cite This
Subhra K. Biswas,
Alberto Mantovani
(2010).
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm.
Nature Immunology
, 11
(10)
, 889-896.
https://doi.org/10.1038/ni.1937
Identifiers
- DOI
- 10.1038/ni.1937