Abstract

Widespread acceptance of a vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will be the next major step in fighting the coronavirus disease 2019 (COVID-19) pandemic, but achieving high uptake will be a challenge and may be impeded by online misinformation. To inform successful vaccination campaigns, we conducted a randomized controlled trial in the UK and the USA to quantify how exposure to online misinformation around COVID-19 vaccines affects intent to vaccinate to protect oneself or others. Here we show that in both countries-as of September 2020-fewer people would 'definitely' take a vaccine than is likely required for herd immunity, and that, relative to factual information, recent misinformation induced a decline in intent of 6.2 percentage points (95th percentile interval 3.9 to 8.5) in the UK and 6.4 percentage points (95th percentile interval 4.0 to 8.8) in the USA among those who stated that they would definitely accept a vaccine. We also find that some sociodemographic groups are differentially impacted by exposure to misinformation. Finally, we show that scientific-sounding misinformation is more strongly associated with declines in vaccination intent.

Keywords

MisinformationVaccinationHerd immunityPandemicCoronavirus disease 2019 (COVID-19)MedicineRandomized controlled trialVaccine efficacyDemographyFamily medicineEnvironmental healthImmunologyDiseasePolitical scienceInternal medicineInfectious disease (medical specialty)

MeSH Terms

AdolescentAdultAgedCOVID-19COVID-19 VaccinesCommunicationFemaleHealth BehaviorHealth KnowledgeAttitudesPracticeHumansImmunityHerdIntentionInternetMaleMiddle AgedSARS-CoV-2United KingdomUnited StatesYoung Adult

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Publication Info

Year
2021
Type
article
Volume
5
Issue
3
Pages
337-348
Citations
1709
Access
Closed

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

1709
OpenAlex
66
Influential

Cite This

Sahil Loomba, Alexandre de Figueiredo, Simon J. Piatek et al. (2021). Measuring the impact of COVID-19 vaccine misinformation on vaccination intent in the UK and USA. Nature Human Behaviour , 5 (3) , 337-348. https://doi.org/10.1038/s41562-021-01056-1

Identifiers

DOI
10.1038/s41562-021-01056-1
PMID
33547453

Data Quality

Data completeness: 86%