Non-haemolytic β-amino-acid oligomers

Emilie A. Porter; Xifang Wang; Hee‐Seung Lee; Bernard Weisblum; Samuel H. Gellman

doi:10.1038/35007145

Keywords

MagaininAntibioticsAntimicrobial peptidesPeptideAntimicrobialBacteriaMicrobiologyOligomerHost (biology)Amino acidBiologyChemistryPathogenic bacteriaBiochemistryEcologyGeneticsOrganic chemistry

Affiliated Institutions

University of Wisconsin–Madison US

Related Publications

Bactericidal Kinetics of 3 Lactoferricins Against Staphylococcus aureus and Escherichia coli

Hilde Ulvatne , Lars H. Vorland

Bovine lactoferricin is an antimicrobial, cationic peptide generated upon gastric pepsin cleavage of bovine lactoferrin. We investigated the bactericidal effects of native lacto...

2001 Scandinavian Journal of Infectious Di... 47 citations

Magainins and the disruption of membrane-linked free-energy transduction.

Hans V. Westerhoff , Davor Juretić , Richard W. Hendler +1 more

Magainins, a family of positively charged peptides, are partly if not wholly responsible for antimicrobial activity in skin extracts of Xenopus laevis. We report here that membe...

1989 Proceedings of the National Academy o... 286 citations

In Vitro Antibacterial Properties of Pexiganan, an Analog of Magainin

Yigong Ge , Dorothy L. MacDonald , Kenneth J. Holroyd +3 more

ABSTRACT Pexiganan, a 22-amino-acid antimicrobial peptide, is an analog of the magainin peptides isolated from the skin of the African clawed frog. Pexiganan exhibited in vitro ...

1999 Antimicrobial Agents and Chemotherapy 352 citations

Structure–activity studies on magainins and other host defense peptides

W. Lee Maloy , U. Prasad Kari

Abstract Host defense peptides are widely distributed in nature, being found in species from bacteria to humans. The structures of these peptides from insects, horseshoe crabs, ...

1995 Biopolymers 486 citations

A novel inducible antibacterial peptide of Drosophila carries an O-glycosylated substitution

Philippe Bulet , J.L. Dimarcq , Charles Hétru +5 more

One of the facets of the host defense of higher insects is the rapid and transient synthesis, following bacterial challenge or trauma, of a battery of potent antibacterial pepti...

1993 Journal of Biological Chemistry 374 citations

Publication Info

Year: 2000
Type: article
Volume: 404
Issue: 6778
Pages: 565-565
Citations: 667
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Non-haemolytic β-amino-acid oligomers

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

667

OpenAlex

Cite This

APA Style

                            
                                
                                    Emilie A. Porter, 
                                
                                    Xifang Wang, 
                                
                                    Hee‐Seung Lee
                                
                                et al.
                            
                            (2000). 
                            Non-haemolytic β-amino-acid oligomers. 
                            Nature
                            , 404
                            (6778)
                            , 565-565.
                            https://doi.org/10.1038/35007145
                        

Identifiers

DOI: 10.1038/35007145