Parallel detection of antigen-specific T cell responses by combinatorial encoding of MHC multimers

Keywords

EpitopeMajor histocompatibility complexAntigenBiologyCD8Flow cytometryBiotinylationMolecular biologyMHC class IStreptavidinT cellImmunologyImmune systemBiochemistryBiotin

Affiliated Institutions

Related Publications

Landscape of tumor-infiltrating T cell repertoire of human cancers

Bo Li , Taiwen Li , Jean‐Christophe Pignon +12 more

2016 Nature Genetics 312 citations

Disruption of the <i>Bcl6</i> Gene Results in an Impaired Germinal Center Formation

Tetsuya Fukuda , Takehiko Yoshida , Seiji Okada +9 more

The Bcl6 gene has been identified from the chromosomal translocation breakpoint in B cell lymphomas, and its products are expressed highly in germinal center (GC) B cells. To in...

1997 The Journal of Experimental Medicine 345 citations

Prognostic value of the CD4+/CD8+ ratio of tumour infiltrating lymphocytes in colorectal cancer and HLA-DR expression on tumour cells

Axel Cosmus Pyndt Diederichsen , Jacob Hjelmborg , Per B. Christensen +2 more

2003 Cancer Immunology Immunotherapy 238 citations

Frequency of regulatory T cells in peripheral blood and in tumour‐infiltrating lymphocytes correlates with poor prognosis in renal cell carcinoma

Francesco Liotta , Mauro Gacci , Francesca Frosali +14 more

What’s known on the subject? and What does the study add? Treg overexpression has been demonstrated in several neoplasms, including liver, breast, pancreas and melanoma, while i...

2010 British Journal of Urology 132 citations

Cancer immunotherapy using checkpoint blockade

Antoni Ribas , Jedd D. Wolchok

The release of negative regulators of immune activation (immune checkpoints) that limit antitumor responses has resulted in unprecedented rates of long-lasting tumor responses i...

2018 Science 6236 citations

Publication Info

Year: 2012
Type: article
Volume: 7
Issue: 5
Pages: 891-902
Citations: 130
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Parallel detection of antigen-specific T cell responses by combinatorial encoding of MHC multimers

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

130

OpenAlex

Cite This

APA Style

                            
                                
                                    Rikke Andersen, 
                                
                                    Pia Kvistborg, 
                                
                                    Thomas Mørch Frøsig
                                
                                et al.
                            
                            (2012). 
                            Parallel detection of antigen-specific T cell responses by combinatorial encoding of MHC multimers. 
                            Nature Protocols
                            , 7
                            (5)
                            , 891-902.
                            https://doi.org/10.1038/nprot.2012.037
                        

Identifiers

DOI: 10.1038/nprot.2012.037