Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study

Barbara Burtness , Kevin J. Harrington , Richard Greil , Barbara Burtness , Kevin J. Harrington , Richard Greil , Denis Soulières , Makoto Tahara , Gilberto de Castro , Amanda Psyrri , Neus Basté , Prakash Neupane , Åse Bratland , Thorsten Fuereder , Brett Hughes , Ricard Mesı́a , Nuttapong Ngamphaiboon , Tamara Rordorf , Wan Zamaniah Wan Ishak , Ruey‐Long Hong , René González Mendoza , Ananya Roy , Yayan Zhang , Burak Gümüşçü , Jonathan D. Cheng , Fan Jin , Danny Rischin , Guillermo Lerzo , Marcelo Tatangelo , Mirta Varela , Juan José Zarbá , Michael Boyer , Hui Gan , Bo Gao , Brett Hughes , Girish Mallesara , Danny Rischin , Anne L. Taylor , Martin Burian , Thorsten Fuereder , Richard Greil , Carlos H. Barrios , Gilberto de Castro , Gilberto de Castro , Fábio Franke , Gustavo Girotto , Iane Pinto Figueiredo Lima , Ulisses Ribaldo Nicolau , Gustavo Dix Junqueira Pinto , Lucas Vieira dos Santos , Ana-Paula Victorino , Neil Chua , Félix Couture , Richard Gregg , Aaron R. Hansen , John Hilton , Joy McCarthy , Denis Soulières , Rodrigo Ascuí , Pablo Gonzalez , Luis J. Villanueva-Rivera , Marco Torregroza , Ángela R. Zambrano , Petra Holeckova , Zdeněk Král , Bohuslav Melichar , Prausova Jana , Milan Vošmik , Maria Andersen , Niels Gyldenkerne , Hannes Jürgens , Kadri Putnik , Petri Reinikainen , Viktor Gruenwald , Simon Laban , Gerasimos Aravantinos , Ioannis Boukovinas , Vassilis Georgoulias , Amanda Psyrri , D.L.W. Kwong , Yousuf Al-Farhat , Tibor Csőszi , József Erfán , Geza Horvai , László Landherr , Éva Remenár , Ágnes Ruzsa , Judit Szota , Salem Billan , Iris Gluck , Orit Gutfeld , Aron Popovtzer , Marco Benasso , Simona Bui , Vittorio Ferrari , Lisa Licitra , Franco Nolè , Takashi Fujii , Yasushi Fujimoto , Nobuhiro Hanai , Hiroki Hara , Koji Matsumoto , Kenji Mitsugi
2019 The Lancet 2,928 citations

Keywords

CetuximabPembrolizumabMedicineChemotherapyHead and neckOncologyOpen labelInternal medicineHead and neck squamous-cell carcinomaHead and neck cancerBasal cellRadiation therapyRandomized controlled trialSurgeryCancerImmunotherapyColorectal cancer

Affiliated Institutions

Related Publications

Publication Info

Year
2019
Type
article
Volume
394
Issue
10212
Pages
1915-1928
Citations
2928
Access
Closed

External Links

Citation Metrics

2928
OpenAlex

Cite This

Barbara Burtness, Kevin J. Harrington, Richard Greil et al. (2019). Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study. The Lancet , 394 (10212) , 1915-1928. https://doi.org/10.1016/s0140-6736(19)32591-7

Identifiers

DOI
10.1016/s0140-6736(19)32591-7