Abstract

SPECT data gathered and analyzed in this manner may be useful as one aspect of the preclinical prediction of AD. Three of the four brain regions important for discriminating Converters from normal controls involve a distributed brain network pertaining to memory, suggesting that this network may be selectively affected in the earliest stages of AD.

Keywords

Spect imagingAlzheimer's Disease Neuroimaging InitiativePosterior cingulateSingle-photon emission computed tomographyThalamusNeuroscienceAnterior cingulate cortexMedicineNeuroimagingInternal medicineAlzheimer's diseaseEmission computed tomographyPerfusionPsychologyNuclear medicineCardiologyCognitionDisease

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Single-photon emission computed tomography

The subject of singl-photon emission computed tomography (SPECT) is generally reviewed. The basic interaction processes of gamma rays in matter are outlined, and the formation o...

1983 Proceedings of the IEEE 63 citations

Publication Info

Year
1998
Type
article
Volume
50
Issue
6
Pages
1563-1571
Citations
465
Access
Closed

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Keith A. Johnson, Kelvyn Jones, B.L. Holman et al. (1998). Preclinical prediction of Alzheimer's disease using SPECT. Neurology , 50 (6) , 1563-1571. https://doi.org/10.1212/wnl.50.6.1563

Identifiers

DOI
10.1212/wnl.50.6.1563