Abstract

The reproducibility of histopathologic classification of breast tumor tissue (nuclear grade) and of axillary lymph nodes (sinus histiocytosis) has been evaluated. In 2 independent readings, an experienced observer assigned 70% of tumor tissue slides and 70% of lymph node slides to the same classification. Two other pathologists agreed fairly well with the classification by the experienced observer. Nuclear grade and sinus histiocytosis were found to be related to patient survival on the basis of classification by each of the 3 pathologists.

Keywords

MedicineReproducibilityBreast cancerLymph nodePathologyLymphAxillary lymph nodesCancerSinus (botany)RadiologyInternal medicine

MeSH Terms

Breast NeoplasmsClassificationFemaleHistiocytesHumansPrognosis

Affiliated Institutions

Related Publications

Publication Info

Year
1966
Type
article
Volume
19
Issue
1
Pages
75-82
Citations
92
Access
Closed

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

92
OpenAlex
0
Influential
66
CrossRef

Cite This

S. J. Cutler, Maurice M. Black, Gilbert H. Friedell et al. (1966). Prognostic factors in cancer of the female breast. II.Reproducibility of histopathologic classification. Cancer , 19 (1) , 75-82. https://doi.org/10.1002/1097-0142(196601)19:1<75::aid-cncr2820190108>3.0.co;2-4

Identifiers

DOI
10.1002/1097-0142(196601)19:1<75::aid-cncr2820190108>3.0.co;2-4
PMID
5901409

Data Quality

Data completeness: 86%