SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2

Keywords

BiologyHeparan sulfateSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakCell biologyBiochemistryCellDiseaseInternal medicineInfectious disease (medical specialty)

Affiliated Institutions

Related Publications

COVID-19 infection: the perspectives on immune responses

Yufang Shi , Ying Wang , Changshun Shao +7 more

More than 100 years since the outbreak of the 1918 influenza pandemic, we now seem to face another pandemic. The outbreak of the new coronavirus (SARS-CoV-2) infection is spread...

2020 Cell Death and Differentiation 1662 citations

The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2

Liang Chen , Xiangjie Li , Mingquan Chen +2 more

Abstract A new type of pneumonia caused by a novel coronavirus SARS-CoV-2 outbreaks recently in China and spreads into many other countries. This disease, named as COVID-19, is ...

2020 Cardiovascular Research 1189 citations

Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection

Jennifer M. Dan , José Mateus , Yu Kato +18 more

Variable memory Immune memory against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) helps to determine protection against reinfection, disease risk, and vaccine e...

2021 Science 2928 citations

Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells

Shutoku Matsuyama , Naganori Nao , Kazuya Shirato +15 more

A novel betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused a large respiratory outbreak in Wuhan, China in December 2019, is currently s...

2020 Proceedings of the National Academy o... 1594 citations

Viral load dynamics and disease severity in patients infected with SARS-CoV-2 in Zhejiang province, China, January-March 2020: retrospective cohort study

Shufa Zheng , Jian‐Gao Fan , Fei Yu +28 more

Abstract Objective To evaluate viral loads at different stages of disease progression in patients infected with the 2019 severe acute respiratory syndrome coronavirus 2 (SARS-Co...

2020 BMJ 1567 citations

Publication Info

Year: 2020
Type: article
Volume: 183
Issue: 4
Pages: 1043-1057.e15
Citations: 1147
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

1147

OpenAlex

Cite This

APA Style

                            
                                
                                    Thomas Mandel Clausen, 
                                
                                    Daniel R. Sandoval, 
                                
                                    Charlotte B. Spliid
                                
                                et al.
                            
                            (2020). 
                            SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. 
                            Cell
                            , 183
                            (4)
                            , 1043-1057.e15.
                            https://doi.org/10.1016/j.cell.2020.09.033
                        

Identifiers

DOI: 10.1016/j.cell.2020.09.033