Abstract
When tissue cells are cultured on very thin sheets of cross-linked silicone fluid, the traction forces the cells exert are made visible as elastic distortion and wrinkling of this substratum. Around explants this pattern of wrinkling closely resembles the "center effects" long observed in plasma clots and traditionally attributed to dehydration shrinkage.
Keywords
WrinkleSilicone rubberTraction (geology)Materials scienceSiliconeComposite materialShrinkageBiophysicsAnatomyBiology
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Publication Info
- Year
- 1980
- Type
- article
- Volume
- 208
- Issue
- 4440
- Pages
- 177-179
- Citations
- 1332
- Access
- Closed
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Cite This
Albert K. Harris,
Patricia Wild,
David Stopak
(1980).
Silicone Rubber Substrata: A New Wrinkle in the Study of Cell Locomotion.
Science
, 208
(4440)
, 177-179.
https://doi.org/10.1126/science.6987736
Identifiers
- DOI
- 10.1126/science.6987736