Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials

Merryn Voysey; Sue Ann Costa Clemens; Shabir A. Madhi; Lily Yin Weckx; Pedro M. Folegatti; Parvinder K. Aley; Brian Angus; Vicky L. Baillie; Shaun Barnabas; Qasim Bhorat; Sagida Bibi; Carmen Briner; Paola Cicconi; Elizabeth Clutterbuck; Andrea M. Collins; Clare Cutland; Thomas C. Darton; Keertan Dheda; Christina Dold; C.J. Duncan; Katherine R. W. Emary; Katie Ewer; Amy Flaxman; Lee Fairlie; Saul N. Faust; Shuo Feng; Daniela M. Ferreira; Adam Finn; Eva Galiza; Anna L. Goodman; Catherine Green; Christopher Green; Melanie Greenland; Catherine Hill; Helen Hill; Ian Hirsch; Alane Izu; Daniel Jenkin; Carina C. D. Joe; Simon Kerridge; Anthonet Koen; Gaurav Kwatra; Rajeka Lazarus; Vincenzo Libri; Patrick Lillie; Natalie G. Marchevsky; Richard P. Marshall; Ana Verena Almeida Mendes; Eveline Pı́polo Milan; Angela M. Minassian; Alastair McGregor; Yama F Mujadidi; Anusha Nana; Sherman D. Padayachee; Daniel J. Phillips; Ana Maria Pittella; Emma Plested; Katrina M. Pollock; Maheshi Ramasamy; Adam Ritchie; Hannah Robinson; Alexandre Vargas Schwarzbold; Darren Smith; Rinn Song; Matthew D. Snape; Eduardo Sprinz; Rebecca Sutherland; Emma C. Thomson; M. Estée Török; Mark Toshner; David P. J. Turner; Johan Vekemans; Tonya Villafana; Thomas White; Christopher J. Williams; Alexander D. Douglas; Adrian V. S. Hill; Teresa Lambe; Sarah C. Gilbert; Andrew J. Pollard; Marites Aban; Kushala W.M. Abeyskera; Jeremy Aboagye; Matthew Adam; Kirsty Adams; James P. Adamson; Gbadebo Adewatan; Syed Adlou; Khatija Ahmed; Yasmeen Akhalwaya; Saajida Akhalwaya; Andrew Alcock; Aabidah Ali; Elizabeth Allen; Lauren Allen; Felipe B. Alvernaz; Fabio Santos Amorim; Claudia Sala Andrade; Foteini Andritsou; Rachel Anslow

doi:10.1016/s0140-6736(21)00432-3

Keywords

MedicineImmunogenicityPlaceboBooster doseInternal medicineRegimenClinical trialRandomized controlled trialImmunologyAntibodyTiterPathology

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Publication Info

Year: 2021
Type: article
Volume: 397
Issue: 10277
Pages: 881-891
Citations: 1195
Access: Closed

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APA Style

                            
                                
                                    Merryn Voysey, 
                                
                                    Sue Ann Costa Clemens, 
                                
                                    Shabir A. Madhi
                                
                                et al.
                            
                            (2021). 
                            Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials. 
                            The Lancet
                            , 397
                            (10277)
                            , 881-891.
                            https://doi.org/10.1016/s0140-6736(21)00432-3
                        

Identifiers

DOI: 10.1016/s0140-6736(21)00432-3