Structure of Functionally Activated Small Ribosomal Subunit

Frank Schluenzen; Ante Tocilj; Raz Zarivach; Joerg Harms; Marco Gluehmann; Daniela Janell; Anat Bashan; Heike Bartels; Ilana Agmon; Ada Yonath

Abstract

Summary particle. It shows known as well as newly detected folding and packing motifs. It provides insight into the deThe small ribosomal subunit performs the decoding coding mechanism and its universality, and highlights of genetic information during translation. The struc- the role of selected components in maintaining the soture of that from Thermus thermophilus shows that phisticated architecture of the ribosome. the decoding center, which positions mRNA and three tRNAs, is constructed entirely of RNA. The entrance to the mRNA channel will encircle the message when Results and Discussion a latch-like contact closes and contributes to processivity and fidelity. Extended RNA helical elements Structure Determination

Keywords

RibosomeThermus thermophilusProofreading30SRibosomal RNARNAComputational biologyProtein subunitGeneticsBiologyCoding regionEukaryotic Large Ribosomal SubunitGenePolymeraseEscherichia coli

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Year: 2000
Type: article
Citations: 330
Access: Closed

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APA Style

                            
                                    Frank Schluenzen, 
                                
                                    Ante Tocilj, 
                                
                                    Raz Zarivach
                                
                                et al.
                            
                            (2000). 
                            Structure of Functionally Activated Small Ribosomal Subunit. 
                            
                            .