Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade

Keywords

BlockadeProgenitor cellCD8ProgenitorImmunologyCytotoxic T cellCancer researchImmune checkpointMedicineBiologyImmunotherapyStem cellImmune systemCell biologyInternal medicineReceptor

MeSH Terms

AnimalsAntibodiesBlockingCD8-Positive T-LymphocytesCell LineTumorFemaleHumansLymphocyte SubsetsLymphocytesTumor-InfiltratingLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMelanomaExperimentalMiceCongenicMiceInbred C57BLProgrammed Cell Death 1 Receptor

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Publication Info

Year: 2019
Type: article
Volume: 20
Issue: 3
Pages: 326-336
Citations: 1853
Access: Closed

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APA Style

                            
                                
                                    Robert T. Manguso, 
                                
                                    F. Stephen Hodi, 
                                
                                    Scott J. Rodig
                                
                                et al.
                            
                            (2019). 
                            Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade. 
                            Nature Immunology
                            , 20
                            (3)
                            , 326-336.
                            https://doi.org/10.1038/s41590-019-0312-6
                        

Identifiers

DOI: 10.1038/s41590-019-0312-6
PMID: 30778252
PMCID: PMC6673650

Data Quality

Data completeness: 72%