The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects*

Abstract

The administration of 5 mug/kg.min dobutamine can improve but not restore capillary perfusion in patients with septic shock. These changes are independent of changes in systemic hemodynamic variables.

Keywords

DobutamineMedicineSeptic shockPerfusionHemodynamicsMicrocirculationShock (circulatory)AnesthesiaCardiologyCapillary refillCardiac indexInternal medicineCardiac outputBlood pressureSepsis

Related Publications

Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: Relationship to hemodynamics, oxygen transport, and survival

Stephen Trzeciak , R. Phillip Dellinger , Joseph E. Parrillo +7 more

2006 Annals of Emergency Medicine 590 citations

Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock

Emanuel P. Rivers , Bryant Nguyen , Suzanne Havstad +5 more

Early goal-directed therapy provides significant benefits with respect to outcome in patients with severe sepsis and septic shock.

2001 New England Journal of Medicine 10623 citations

Before–after study of a standardized hospital order set for the management of septic shock*

Scott T. Micek , Nareg H. Roubinian , Tim Heuring +7 more

Our study found that the implementation of a standardized order set for the management of septic shock in the emergency department was associated with statistically more rigorou...

2006 Critical Care Medicine 375 citations

Cardiovascular management of septic shock

R. Phillip Dellinger

From Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Section of Critical Care Medicine, Cooper Health System, Camden, NJ. Address request...

2003 Critical Care Medicine 372 citations

Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock

R. Phillip Dellinger , Jean Carlet , Henry Masur +11 more

OBJECTIVE: In 2003, critical care and infectious disease experts representing 11 international organizations developed management guidelines for severe sepsis and septic shock t...

2004 Critical Care Medicine 3022 citations

Publication Info

Year: 2006
Type: article
Volume: 34
Issue: 2
Pages: 403-408
Citations: 483
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects*

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

483

OpenAlex

Cite This

APA Style

                            
                                
                                    Daniel De Backer, 
                                
                                    Jacques Créteur, 
                                
                                    Marc‐Jacques Dubois
                                
                                et al.
                            
                            (2006). 
                            The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects*. 
                            Critical Care Medicine
                            , 34
                            (2)
                            , 403-408.
                            https://doi.org/10.1097/01.ccm.0000198107.61493.5a
                        

Identifiers

DOI: 10.1097/01.ccm.0000198107.61493.5a