The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet

C. Anders Olson; Helen E. Vuong; Jessica M. Yano; Qingxing Y. Liang; David J. Nusbaum; Elaine Y. Hsiao

doi:10.1016/j.cell.2018.04.027

Keywords

Ketogenic dietAkkermansiaBiologyGut floraEpilepsyNeuroprotectionGlutamate receptorAnticonvulsantHippocampal formationImmunologyPharmacologyEndocrinologyInternal medicineBiochemistryNeuroscienceLactobacillusBacteriaReceptorMedicineGenetics

Affiliated Institutions

University of California, Los Angeles US

Related Publications

The Influence of Probiotics on the Firmicutes/Bacteroidetes Ratio in the Treatment of Obesity and Inflammatory Bowel disease

Spase Stojanov , Aleš Berlec , Borut Štrukelj

The two most important bacterial phyla in the gastrointestinal tract, Firmicutes and Bacteroidetes, have gained much attention in recent years. The Firmicutes/Bacteroidetes (F/B...

2020 Microorganisms 1690 citations

Probiotics and prebiotics in intestinal health and disease: from biology to the clinic

Mary Ellen Sanders , Daniel Merenstein , Gregor Reid +2 more

Probiotics and prebiotics are microbiota-management tools for improving host health. They target gastrointestinal effects via the gut, although direct application to other sites...

2019 Nature Reviews Gastroenterology & Hep... 1775 citations

Role of gut microbiota in type 2 diabetes pathophysiology

Manoj Gurung , Zhipeng Li , Hannah You +4 more

A substantial body of literature has provided evidence for the role of gut microbiota in metabolic diseases including type 2 diabetes. However, reports vary regarding the associ...

2020 EBioMedicine 1559 citations

Microbial tryptophan catabolites in health and disease

Henrik M. Roager , Tine Rask Licht

Accumulating evidence implicates metabolites produced by gut microbes as crucial mediators of diet-induced host-microbial cross-talk. Here, we review emerging data suggesting th...

2018 Nature Communications 1841 citations

Human gut microbiome: hopes, threats and promises

Patrice D. Cani

The microbiome has received increasing attention over the last 15 years. Although gut microbes have been explored for several decades, investigations of the role of microorganis...

2018 Gut 1296 citations

Publication Info

Year: 2018
Type: article
Volume: 173
Issue: 7
Pages: 1728-1741.e13
Citations: 982
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

982

OpenAlex

Cite This

APA Style

                            
                                
                                    C. Anders Olson, 
                                
                                    Helen E. Vuong, 
                                
                                    Jessica M. Yano
                                
                                et al.
                            
                            (2018). 
                            The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet. 
                            Cell
                            , 173
                            (7)
                            , 1728-1741.e13.
                            https://doi.org/10.1016/j.cell.2018.04.027
                        

Identifiers

DOI: 10.1016/j.cell.2018.04.027