Abstract

Orthologs and paralogs are two fundamentally different types of homologous genes that evolved, respectively, by vertical descent from a single ancestral gene and by duplication. Orthology and paralogy are key concepts of evolutionary genomics. A ...Read More

Keywords

BiologyGene duplicationGeneticsGeneHomologous chromosomeGenomicsEvolutionary biologyComparative genomicsGenomeMolecular evolutionComputational biology

Affiliated Institutions

Related Publications

Publication Info

Year
1984
Type
review
Volume
18
Issue
1
Pages
553-612
Citations
763
Access
Closed

External Links

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

763
OpenAlex

Cite This

Harold Varmus (1984). THE MOLECULAR GENETICS OF CELLULAR ONCOGENES. Annual Review of Genetics , 18 (1) , 553-612. https://doi.org/10.1146/annurev.ge.18.120184.003005

Identifiers

DOI
10.1146/annurev.ge.18.120184.003005