Abstract

The Protein Ontology (PRO) provides a formal, logically-based classification of specific protein classes including structured representations of protein isoforms, variants and modified forms. Initially focused on proteins found in human, mouse and Escherichia coli, PRO now includes representations of protein complexes. The PRO Consortium works in concert with the developers of other biomedical ontologies and protein knowledge bases to provide the ability to formally organize and integrate representations of precise protein forms so as to enhance accessibility to results of protein research. PRO (http://pir.georgetown.edu/pro) is part of the Open Biomedical Ontology Foundry.

Keywords

BiologyOntologyRepresentation (politics)Computational biologyOpen Biomedical OntologiesProcess ontologyBioinformaticsComputer scienceInformation retrievalSuggested Upper Merged OntologySemantic Web

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Publication Info

Year
2010
Type
article
Volume
39
Issue
Database
Pages
D539-D545
Citations
146
Access
Closed

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Darren A. Natale, Cecilia Arighi, Winona C. Barker et al. (2010). The Protein Ontology: a structured representation of protein forms and complexes. Nucleic Acids Research , 39 (Database) , D539-D545. https://doi.org/10.1093/nar/gkq907

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DOI
10.1093/nar/gkq907