Abstract
Abstract The PSIPRED Workbench is a web server offering a range of predictive methods to the bioscience community for 20 years. Here, we present the work we have completed to update the PSIPRED Protein Analysis Workbench and make it ready for the next 20 years. The main focus of our recent website upgrade work has been the acceleration of analyses in the face of increasing protein sequence database size. We additionally discuss any new software, the new hardware infrastructure, our webservices and web site. Lastly we survey updates to some of the key predictive algorithms available through our website.
Keywords
WorkbenchBiologySoftwareFocus (optics)Web serverWeb applicationKey (lock)Web serviceWorld Wide WebThe InternetComputer scienceVisualizationOperating systemData mining
Affiliated Institutions
Related Publications
Ensembl 2015
Ensembl (http://www.ensembl.org) is a genomic interpretation system providing the most up-to-date annotations, querying tools and access methods for chordates and key model orga...
Ensembl 2020
Abstract The Ensembl (https://www.ensembl.org) is a system for generating and distributing genome annotation such as genes, variation, regulation and comparative genomics across...
SIFT web server: predicting effects of amino acid substitutions on proteins
The Sorting Intolerant from Tolerant (SIFT) algorithm predicts the effect of coding variants on protein function. It was first introduced in 2001, with a corresponding website t...
IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding
The structural states of proteins include ordered globular domains as well as intrinsically disordered protein regions that exist as highly flexible conformational ensembles in ...
SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling
Abstract Comparative protein modeling is increasingly gaining interest since it is of great assistance during the rational design of mutagenesis experiments. The availability of...
Publication Info
- Year
- 2019
- Type
- article
- Volume
- 47
- Issue
- W1
- Pages
- W402-W407
- Citations
- 1336
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
1336
OpenAlex
Cite This
Daniel Buchan,
David T. Jones
(2019).
The PSIPRED Protein Analysis Workbench: 20 years on.
Nucleic Acids Research
, 47
(W1)
, W402-W407.
https://doi.org/10.1093/nar/gkz297
Identifiers
- DOI
- 10.1093/nar/gkz297