Abstract

SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotations (such as the description of the function of a protein, structure of its domains, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases. Recent developments of the database include: an increase in the number and scope of model organisms; cross-references to two additional databases; a variety of new documentation files and the creation of TrEMBL, a computer annotated supplement to SWISS-PROT. This supplement consists of entries in SWISS-PROT-like format derived from the translation of all coding sequences (CDS) in the EMBL nucleotide sequence database, except the CDS already included in SWISS-PROT.

Keywords

UniProtBiologyDocumentationSequence databaseProtein sequencingProtein Data BankComputational biologySequence (biology)Data bankRedundancy (engineering)BioinformaticsDatabaseProtein structurePeptide sequenceGeneticsComputer scienceProgramming languageBiochemistryGene

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Related Publications

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Amos Bairoch

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Publication Info

Year
1997
Type
article
Volume
25
Issue
1
Pages
31-36
Citations
731
Access
Closed

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Amos Bairoch, Rolf Apweiler (1997). The SWISS-PROT protein sequence data bank and its supplement TrEMBL. Nucleic Acids Research , 25 (1) , 31-36. https://doi.org/10.1093/nar/25.1.31

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DOI
10.1093/nar/25.1.31