Consensus methods: characteristics and guidelines for use.
Consensus methods are being used increasingly to solve problems in medicine and health. Their main purpose is to define levels of agreement on controversial subjects. Advocates ...
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1,857 publications
GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes
An important assessment prior to genome assembly and related analyses is genome profiling, where the k-mer frequencies within raw sequencing reads are analyzed to estimate major...
Purification and Characterization of Hypoxia-inducible Factor 1
Hypoxia-inducible factor 1 (HIF-1) is a DNA-binding protein that activates erythropoietin (Epo) gene transcription in Hep3B cells subjected to hypoxia or cobalt chloride treatme...
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
Abstract Objective Develop a cerebrospinal fluid biomarker signature for mild Alzheimer's disease (AD) in Alzheimer's Disease Neuroimaging Initiative (ADNI) subjects. Methods Am...
How to Read and Interpret FTIR Spectroscope of Organic Material
Fourier Transform Infrared (FTIR) has been developed as a tool for the simultaneous and quantitative determination of organic components, including chemical bond, as well as org...
Use and Misuse of the Receiver Operating Characteristic Curve in Risk Prediction
The c statistic, or area under the receiver operating characteristic (ROC) curve, achieved popularity in diagnostic testing, in which the test characteristics of sensitivity and...
The Association of Changes in Physical-Activity Level and Other Lifestyle Characteristics with Mortality among Men
Beginning moderately vigorous sports activity, quitting cigarette smoking, maintaining normal blood pressure, and avoiding obesity were separately associated with lower rates of...
Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2
In this case series of hospitalized children who met criteria for PIMS-TS, there was a wide spectrum of presenting signs and symptoms and disease severity, ranging from fever an...
Using Artificial Intelligence to Detect COVID-19 and Community-acquired Pneumonia Based on Pulmonary CT: Evaluation of the Diagnostic Accuracy
Background Coronavirus disease 2019 (COVID-19) has widely spread all over the world since the beginning of 2020. It is desirable to develop automatic and accurate detection of C...
New families in the classification of glycosyl hydrolases based on amino acid sequence similarities
301 glycosyl hydrolases and related enzymes corresponding to 39 EC entries of the I.U.B. classification system have been classified into 35 families on the basis of amino-acid-s...