p53 Mutations in Human Cancers
Mutations in the evolutionarily conserved codons of the p53 tumor suppressor gene are common in diverse types of human cancer. The p53 mutational spectrum differs among cancers ...
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6,044 publications
3D Slicer as an image computing platform for the Quantitative Imaging Network
Quantitative analysis has tremendous but mostly unrealized potential in healthcare to support objective and accurate interpretation of the clinical imaging. In 2008, the Nationa...
Dexamethasone in Hospitalized Patients with Covid-19.
BACKGROUND: Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progres...
The self-organizing map
The self-organized map, an architecture suggested for artificial neural networks, is explained by presenting simulation experiments and practical applications. The self-organizi...
Construction of <i>Escherichia coli</i> K‐12 in‐frame, single‐gene knockout mutants: the Keio collection
We have systematically made a set of precisely defined, single‐gene deletions of all nonessential genes in Escherichia coli K‐12. Open‐reading frame coding regions were replaced...
Control of Regulatory T Cell Development by the Transcription Factor <i>Foxp3</i>
Regulatory T cells engage in the maintenance of immunological self-tolerance by actively suppressing self-reactive lymphocytes. Little is known, however, about the molecular mec...
Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration
Much medical research is observational. The reporting of observational studies is often of insufficient quality. Poor reporting hampers the assessment of the strengths and weakn...
The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions.
OBJECTIVE: To test the feasibility of creating a valid and reliable checklist with the following features: appropriate for assessing both randomised and non-randomised studies; ...
Overview of the H.264/AVC video coding standard
H.264/AVC is newest video coding standard of the ITU-T Video Coding Experts Group and the ISO/IEC Moving Picture Experts Group. The main goals of the H.264/AVC standardization e...
Mind the Gap: Why do people act environmentally and what are the barriers to pro-environmental behavior?
Abstract Numerous theoretical frameworks have been developed to explain the gap between the possession of environmental knowledge and environmental awareness, and displaying pro...
Applications of case study research
Theory The Role of Theory in Doing Case Studies What is the Case Study Method? What is the Role of Theory in Doing Case Studies Exploratory Case Studies Case Selection and Scree...
Quantum Fields in Curved Space
This book presents a comprehensive review of the subject of gravitational effects in quantum field theory. Although the treatment is general, special emphasis is given to the Ha...