Atoms in Molecules
Abstract The molecular structure hypothesis - that a molecule is a collection of atoms linked by a network of bonds - was forged in the crucible of nineteenth-century experiment...
Publications
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5,192 publications
Role of Insulin Resistance in Human Disease
Resistance to insulin-stimulated glucose uptake is present in the majority of patients with impaired glucose tolerance (IGT) or non-insulin-dependent diabetes mellitus (NIDDM) a...
Stages of embryonic development of the zebrafish
Abstract We describe a series of stages for development of the embryo of the zebrafish, Danio (Brachydanio) rerio . We define seven broad periods of embryogenesis—the zygote, cl...
Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments
The problem of identifying differentially expressed genes in designed microarray experiments is considered. Lonnstedt and Speed (2002) derived an expression for the posterior od...
Bayes Factors
Abstract In a 1935 paper and in his book Theory of Probability, Jeffreys developed a methodology for quantifying the evidence in favor of a scientific theory. The centerpiece wa...
Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene
The HER-2/ neu oncogene is a member of the erb B-like oncogene family, and is related to, but distinct from, the epidermal growth factor receptor. This gene has been shown to be...
Tissue Plasminogen Activator for Acute Ischemic Stroke
Thrombolytic therapy for acute ischemic stroke has been approached cautiously because there were high rates of intracerebral hemorrhage in early clinical trials. We performed a ...
A training algorithm for optimal margin classifiers
A training algorithm that maximizes the margin between the training patterns and the decision boundary is presented. The technique is applicable to a wide variety of the classif...
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
Patients with type 2 diabetes at high risk for cardiovascular events who received empagliflozin, as compared with placebo, had a lower rate of the primary composite cardiovascul...
Aggregated Residual Transformations for Deep Neural Networks
We present a simple, highly modularized network architecture for image classification. Our network is constructed by repeating a building block that aggregates a set of transfor...
Telling more than we can know: Verbal reports on mental processes.
Evidence is reviewed which suggests that there may be little or no direct introspective access to higher order cognitive processes. Subjects are sometimes (a) unaware of the exi...
A survey on Image Data Augmentation for Deep Learning
Abstract Deep convolutional neural networks have performed remarkably well on many Computer Vision tasks. However, these networks are heavily reliant on big data to avoid overfi...