Publications
Explore 153 academic publications
Intraepithelial CD8<sup>+</sup>tumor-infiltrating lymphocytes and a high CD8<sup>+</sup>/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer
In a recent report, [Zhang et al. (2003) N. Engl. J. Med. 348, 203–213], the presence of CD3 + tumor-infiltrating lymphocytes (TILs) was found to correlate with improved surviva...
Critical Issues in Qualitative Research Methods.
Dialogue On Origins Qualitative Research - Janice M Morse Fact or Fantasy? Dialogue On Learning Qualitative Methods Abstract Knowing - Katharyn A May The Case for Magic in Metho...
Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study
Canadian Institutes of Health Research, Heart and Stroke Foundation of Canada, Canadian Stroke Network, Health Research Board Ireland, Swedish Research Council, Swedish Heart an...
Age and the Explanation of Crime
One of the few facts agreed on in criminology is the age distribution of crime. This fact has been used to criticize social theories of crime causation, to provide the foundatio...
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
Most patients with acute myeloid leukaemia (AML) die from progressive disease after relapse, which is associated with clonal evolution at the cytogenetic level. To determine the...
The Sanger FASTQ file format for sequences with quality scores, and the Solexa/Illumina FASTQ variants
FASTQ has emerged as a common file format for sharing sequencing read data combining both the sequence and an associated per base quality score, despite lacking any formal defin...
Gene-Expression Profiles in Hereditary Breast Cancer
Significantly different groups of genes are expressed by breast cancers with BRCA1 mutations and breast cancers with BRCA2 mutations. Our results suggest that a heritable mutati...
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole-genome sequencing of 12 ETP ALL cases and...
International Prevalence, Recognition, and Treatment of Cardiovascular Risk Factors in Outpatients With Atherothrombosis
This large, international, contemporary database shows that classic cardiovascular risk factors are consistent and common but are largely undertreated and undercontrolled in man...