Autophagy fights disease through cellular self-digestion
Autophagy, or cellular self-digestion, is a cellular pathway involved in protein and organelle degradation, with an astonishing number of connections to human disease and physio...
Publications
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1,782 publications
The socio-economic implications of the coronavirus pandemic (COVID-19): A review
The COVID-19 pandemic has resulted in over 4.3 million confirmed cases and over 290,000 deaths globally. It has also sparked fears of an impending economic crisis and recession....
Dimensionalizing Cultures: The Hofstede Model in Context
Submitted by Celso Magalhaes (celsomagalhaes@ufrrj.br) on 2018-07-27T14:34:23Z \nNo. of bitstreams: 1 \n2017 - Sheila Maria de Souza Santos.pdf: 2668707 bytes, checksum:...
2016 European Guidelines on cardiovascular disease prevention in clinical practice
The ESC Guidelines represent the views of the ESC and were produced after careful consideration of the scientific and medical knowledge and the evidence available at \nthe t...
2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides
2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides J. Jennette;R. Falk;P. Bacon;N. Basu;M. Cid;F. Ferrario;L. Flores-Suarez;W. Gross;L. Gu...
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
The role of the adaptive immune response in controlling the growth and recurrence of human tumors has been controversial. We characterized the tumor-infiltrating immune cells in...
Structural Equation Modeling and Regression: Guidelines for Research Practice
The growing interest in Structured Equation Modeling (SEM) techniques and recognition of their importance in IS research raises the need to compare and contrast the different ty...
Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer
In patients with previously untreated metastatic nonsquamous NSCLC without EGFR or ALK mutations, the addition of pembrolizumab to standard chemotherapy of pemetrexed and a plat...
Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction
BACKGROUND In patients with type 2 diabetes, inhibitors of sodium-glucose cotransporter 2 (SGLT2) reduce the risk of a first hospitalization for heart failure, possibly through ...
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.
Several polycations possessing substantial buffering capacity below physiological pH, such as lipopolyamines and polyamidoamine polymers, are efficient transfection agents per s...