Copper induces cell death by targeting lipoylated TCA cycle proteins
Copper is an essential cofactor for all organisms, and yet it becomes toxic if concentrations exceed a threshold maintained by evolutionarily conserved homeostatic mechanisms. H...
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283 publications
Diagnosis of Idiopathic Pulmonary Fibrosis. An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline
The guideline panel provided recommendations related to the diagnosis of IPF.
Some Methods for Strengthening the Common χ 2 Tests
Since the x2 tests of goodness of fit and of association in contingency tables are presented in many courses on statistical methods for beginners in the subject, it is not surpr...
The Gene Ontology resource: enriching a GOld mine
Abstract The Gene Ontology Consortium (GOC) provides the most comprehensive resource currently available for computable knowledge regarding the functions of genes and gene produ...
SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules
Abstract SwissTargetPrediction is a web tool, on-line since 2014, that aims to predict the most probable protein targets of small molecules. Predictions are based on the similar...
Cancer treatment and survivorship statistics, 2022
Abstract The number of cancer survivors continues to increase in the United States due to the growth and aging of the population as well as advances in early detection and treat...
An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
The mRNA-1273 vaccine induced anti-SARS-CoV-2 immune responses in all participants, and no trial-limiting safety concerns were identified. These findings support further develop...
GEOquery: a bridge between the Gene Expression Omnibus (GEO) and BioConductor
Abstract Microarray technology has become a standard molecular biology tool. Experimental data have been generated on a huge number of organisms, tissue types, treatment conditi...