Mitochondrial disease in mouse results in increased oxidative stress
It has been hypothesized that a major factor in the progression of mitochondrial disease resulting from defects in oxidative phosphorylation (OXPHOS) is the stimulation of the m...
Publications
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220 publications
Maternal Attachment
Abstract To determine whether present hospital practices may affect later maternal behavior, we placed 28 primiparous women in two study groups shortly after delivery of normal ...
Mental illness in general health care : an international study
Partial table of contents: The Background and Rationale of the WHO Collaborative Sudy on 'Psychological Problems in General Health Care' (T. ?st?n & N. Sartiorius). Methods of t...
Functional anatomy of human procedural learning determined with regional cerebral blood flow and PET
The functional anatomy of motor skill acquisition was investigated in six normal human subjects who learned to perform a pursuit rotor task with their dominant right hand during...
Wheezing, asthma, and pulmonary dysfunction 10 years after infection with respiratory syncytial virus in infancy.
Of the 180 children admitted to hospitals in Tyneside in the first year of life with proved respiratory syncytial virus lower respiratory tract infection, 130 were seen for revi...
Implementation of a bundle of quality indicators for the early management of severe sepsis and septic shock is associated with decreased mortality*
Implementation of a severe sepsis bundle using a quality improvement feedback to modify physician behavior in the emergency department setting was feasible and was associated wi...
Assemblathon 1: A competitive assessment of de novo short read assembly methods
Low-cost short read sequencing technology has revolutionized genomics, though it is only just becoming practical for the high-quality de novo assembly of a novel large genome. W...
Database resources of the National Center for Biotechnology Information
In addition to maintaining the GenBank® nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for th...
Clinical Features and Short-term Outcomes of 102 Patients with Coronavirus Disease 2019 in Wuhan, China
Abstract Background In December 2019, a series of pneumonia cases of unknown cause emerged in Wuhan, Hubei, China. In this study, we investigate the clinical and laboratory feat...
Gender-Related Differences in Acute Aortic Dissection
Background— Few data exist on gender-related differences in clinical presentation, diagnostic findings, management, and outcomes in acute aortic dissection (AAD). Methods and Re...
Consistency of the burnout construct across occupations
Abstract This study assessed the extent to which a recently developed measure of burnout extended the concept of burnout as developed among human service providers to people in ...
The Importance of Co-existent Disease in the Occurrence of Postoperative Complications and One-Year Recovery in Patients Undergoing Total Hip Replacement
Co-existent or comorbid diseases are appreciated as prognostic factors in studies of quality and effectiveness of care when mortality is the end point. The need to measure and a...