Functional profiling of the Saccharomyces cerevisiae genome
Determining the effect of gene deletion is a fundamental approach to understanding gene function. Conventional genetic screens exhibit biases, and genes contributing to a phenot...
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Methods for integrating moderation and mediation: A general analytical framework using moderated path analysis.
Studies that combine moderation and mediation are prevalent in basic and applied psychology research. Typically, these studies are framed in terms of moderated mediation or medi...
Chemical and Electrochemical Electron-Transfer Theory
One of the active areas in reaction kinetics during the post-war years has \nbeen that of electron-transfer reactions. These reactions constitute one type \nof oxidation...
Cancer treatment and survivorship statistics, 2019
Abstract The number of cancer survivors continues to increase in the United States because of the growth and aging of the population as well as advances in early detection and t...
Chemical Sensors Based on Amplifying Fluorescent Conjugated Polymers
ADVERTISEMENT RETURN TO ISSUEPREVArticleChemical Sensors Based on Amplifying Fluorescent Conjugated PolymersSamuel W. Thomas, Guy D. Joly, and Timothy M. SwagerView Author Infor...
Modified RECIST (mRECIST) Assessment for Hepatocellular Carcinoma
The endpoint in cancer research is overall survival. Nonetheless, other potential surrogate endpoints, such as response rate and time to progression, are currently used. Measure...
Cancer Statistics, 2004
Each year, the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on...
Erlotinib Plus Gemcitabine Compared With Gemcitabine Alone in Patients With Advanced Pancreatic Cancer: A Phase III Trial of the National Cancer Institute of Canada Clinical Trials Group
Purpose Patients with advanced pancreatic cancer have a poor prognosis and there have been no improvements in survival since the introduction of gemcitabine in 1996. Pancreatic ...
Transtheoretical therapy: Toward a more integrative model of change.
Transtheoretical therapy is presented as one alternative within the Zeitgeist seeking a synthesis for the increasing proliferation of therapeutic systems. From a comparative ana...
The Pfam protein families database
Pfam is a widely used database of protein families, currently containing more than 13 000 manually curated protein families as of release 26.0. Pfam is available via servers in ...
Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease
We found that autosomal dominant Alzheimer's disease was associated with a series of pathophysiological changes over decades in CSF biochemical markers of Alzheimer's disease, b...