Publications

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

Integrating single-cell transcriptomic data across different conditions, technologies, and species

The Sequence of the Human Genome

A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp ...

Modernity and Self-Identity: Self and Society in the Late Modern Age

The reflexivity of modernity extends into core of the self. Put in another way, in the context of a post-traditional order, the self becomes a reflexive project. One concerns th...

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

The Gene Expression Omnibus (GEO) project was initiated in response to the growing demand for a public repository for high-throughput gene expression data. GEO provides a flexib...

The blockade of immune checkpoints in cancer immunotherapy

Obesity: preventing and managing the global epidemic. Report of a WHO consultation.

Overweight and obesity represent a rapidly growing threat to the health of populations in an increasing number of countries. Indeed they are now so common that they are replacin...

Rectified Linear Units Improve Restricted Boltzmann Machines

Restricted Boltzmann machines were developed using binary stochastic hidden units. These can be generalized by replacing each binary unit by an infinite number of copies that al...

Robust enumeration of cell subsets from tissue expression profiles

We introduce CIBERSORT, a method for characterizing cell composition of complex tissues from their gene expression profiles. When applied to enumeration of hematopoietic subsets...

Twelve years of SAMtools and BCFtools

Abstract Background SAMtools and BCFtools are widely used programs for processing and analysing high-throughput sequencing data. They include tools for file format conversion an...