Bruce Wightman - Researcher Profile | RDL Research Database

Publications

3 shown

A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation.

Ilho Ha , Bruce Wightman , Gary Ruvkun

The Caenorhabditis elegans heterochronic gene lin-14 generates a temporal gradient of the LIN-14 proteins to control stage-specific patterns of cell lineage during development. ...

1996 Genes & Development 233 citations

Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development.

Bruce Wightman , Thomas R. Bürglin , Jared Gatto +2 more

The heterchronic gene lin-14 controls the temporal sequence of developmental events in the Caenorhabditis elegans postembryonic cell lineage. It encodes a nuclear protein that n...

1991 Genes & Development 209 citations

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

Bruce Wightman , Ilho Ha , Gary Ruvkun

1993 Cell 4171 citations

Frequent Co-Authors

Researcher Info

h-index: 3
Publications: 3
Citations: 4,613
Institution: Massachusetts General Hospital

External Links

ORCID Profile Google Scholar

Identifiers

ORCID: 0000-0001-7811-8760

Impact Metrics

h-index 3

h-index: Number of publications with at least h citations each.