Deborah J. Cook

Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement

Evaluating Meta-analyses in the General Surgical Literature

This critical appraisal of meta-analyses published in the general surgery literature demonstrates frequent methodologic flaws. The quality of these reports limits the validity o...

2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference

This document reflects a process whereby a group of experts and opinion leaders revisited the 1992 sepsis guidelines and found that apart from expanding the list of signs and sy...

Randomized trials stopped early for benefit: a systematic review.

RCTs stopped early for benefit are becoming more common, often fail to adequately report relevant information about the decision to stop early, and show implausibly large treatm...

Multiple Organ Dysfunction Score

This multiple organ dysfunction score, constructed using simple physiologic measures of dysfunction in six organ systems, mirrors organ dysfunction as the intensivist sees it an...

From the bench to the bedside: the future of sepsis research. Executive summary of an American College of Chest Physicians, National Institute of Allergy and Infectious Disease, and National Heart, Lung, and Blood Institute Workshop.

A systematic review and meta-analysis of studies comparing mortality rates of private for-profit and private not-for-profit hospitals.

Our meta-analysis suggests that private for-profit ownership of hospitals, in comparison with private not-for-profit ownership, results in a higher risk of death for patients.