Dominik Witzigmann - Researcher Profile

Publications

5 shown

On the role of helper lipids in lipid nanoparticle formulations of siRNA

Jayesh A. Kulkarni , Dominik Witzigmann , Jerry Leung +2 more

In empty LNP formulations, DSPC–cholesterol resides in outer layers, whereas in loaded systems some of the DSPC–cholesterol is internalized together with siRNA.

2019 Nanoscale 344 citations

Rapid optimization of liposome characteristics using a combined microfluidics and design-of-experiment approach

Mahsa Sedighi , Sandro Sieber , Fereshteh Rahimi +4 more

2018 Drug Delivery and Translational Research 100 citations

mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability

Linde Schoenmaker , Dominik Witzigmann , Jayesh A. Kulkarni +4 more

2021 International Journal of Pharmaceutics 1293 citations

The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

Akin Akinc , Martin A. Maier , Muthiah Manoharan +15 more

2019 Nature Nanotechnology 1398 citations

The current landscape of nucleic acid therapeutics

Jayesh A. Kulkarni , Dominik Witzigmann , Sarah B. Thomson +4 more

2021 Nature Nanotechnology 1147 citations

Frequent Co-Authors

Researcher Info

h-index: 5
Publications: 5
Citations: 4,282
Institution: University of British Columbia

External Links

ORCID Profile Google Scholar

Identifiers

ORCID: 0000-0002-8197-8558

Impact Metrics

h-index 5

h-index: Number of publications with at least h citations each.