The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

Akin Akinc; Martin A. Maier; Muthiah Manoharan; Kevin Fitzgerald; Muthusamy Jayaraman; Scott Barros; Steven M. Ansell; Xinyao Du; Michael J. Hope; Thomas D. Madden; Barbara L. Mui; Sean C. Semple; Ying K. Tam; Marco A. Ciufolini; Dominik Witzigmann; Jayesh A. Kulkarni; Roy van der Meel; Pieter R. Cullis

doi:10.1038/s41565-019-0591-y

Keywords

Nucleic acidTranslation (biology)NanotechnologySmall interfering RNADrug deliveryRNATransthyretinChemistryDrugNanoparticleComputational biologyBiochemistryPharmacologyMedicineMaterials scienceBiologyPathologyGene

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Publication Info

Year: 2019
Type: article
Volume: 14
Issue: 12
Pages: 1084-1087
Citations: 1398
Access: Closed

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APA Style

                            
                                
                                    Akin Akinc, 
                                
                                    Martin A. Maier, 
                                
                                    Muthiah Manoharan
                                
                                et al.
                            
                            (2019). 
                            The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs. 
                            Nature Nanotechnology
                            , 14
                            (12)
                            , 1084-1087.
                            https://doi.org/10.1038/s41565-019-0591-y
                        

Identifiers

DOI: 10.1038/s41565-019-0591-y